阿德福韦酯致范科尼综合征合并低磷性骨软化症及代谢性酸中毒1例报告
范科尼综合征是近端肾小管复合型功能缺陷引起多种溶质随尿排泄过多而导致的临床综合征,临床突出表现为:尿液出现过量氨基酸、葡萄糖、磷酸盐、碳酸盐、尿酸盐等,内环境则出现低血磷、低血钾、低血钙、低尿酸及酸中毒,以及骨软化、骨质疏松等骨骼病变。而药物引起的范可尼综合征可能被忽视或误诊,这增加了病人的痛苦的程度。我院收治1例阿德福韦酯致范科尼综合征合并低磷性骨软化症及代谢性酸中毒,应引起临床重视。
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