Volume 3,Issue 9
芦荟大黄素抗肿瘤药理作用及其分子机制研究进展
芦荟大黄素（Aloe-emodin，AE）是一种天然蒽醌类化合物，广泛存在于大黄属和芦荟等药用植物中。研究表明，它具有显著的抗肿瘤活性，其作用机制涉及多种信号通路和分子靶点，能够通过抑制肿瘤细胞增殖、诱导凋亡和焦亡、阻碍迁移与侵袭、抑制肿瘤血管生成，以及调控肿瘤微环境等途径发挥抗癌效应。本文基于国内外AE的抗肿瘤研究相关文献，对其抗肿瘤药理作用及分子机制进行归纳分析，以期为AE的进一步研发和应用提供参考。
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