[1] Song MS,Pandolfi PP.The HECT family of E3 ubiquitin ligases and PTEN［J］．Semin Cancer Biol, 2022，85:43-51.PMID: 34129913.
[2] Konopleva M, Martinelli G, Daver N, et al. MDM2 inhibition: an importantstep forward in cancer therapy［J］．Leukemia, 2020，34(11):2858-2874. PMID:32651541.
[3] Gupta P,Zhao H,Hoang B,et al. Targeting the untargetable: RB1-deficienttumours are vulnerable to Skp2 ubiquitin ligase inhibition［J］．Br J Cancer, 2022，127(6):969-975.PMID: 35752713.
[4] Zhao H,Bi F,Li M,et al. E3 ubiquitin ligase RNF180 impairs IPO4/SOX2 complexstability and inhibits SOX2-mediated malignancy in ovarian cancer［J］．CellSignal,2024，113:110961. PMID: 37923100.
[5] Di Fiore R,Suleiman S,Drago-Ferrante R,et al.The Role of FBXW7 inGynecologic Malignancies［J］．Cells,2023,12(10):1415.PMID: 37408248.
[6] Sun X,Ye G,Li J,et al.Parkin regulates IGF2BP3 through ubiquitination in thetumourigenesis of cervical cancer ［J］．Clin Transl Med,2023,13(10):e1457. PMID:37877353
[7] Lee J,Zhou P.DCAFs.The missing link of the CUL4-DDB1 ubiquitin ligase［J］．Mol Cell,2007,26(6):775-780.PMID: 17588513.
[8] Yang Q, Zhao J, Chen D, et al. E3 ubiquitin ligases: styles, structures andfunctions［J］． Mol Biomed. 2021，2(1):23. PMID: 35006464.
[9] Xiaonan Zhang,Stig Linder,Martina Bazzaro.Drug Development Targeting theUbiquitin–Proteasome System (UPS) for the Treatment of Human Cancers［J］．Cancers,2020,12(4):902.PMID: 32272746.
[10] Watson ER, Brown NG, Peters JM, et al .Posing the APC/C E3 Ubiquitin Ligaseto Orchestrate Cell Division［J］．Trends Cell Biol,2019，29(2):117-134.PMID:30482618.
[11] You S, Xu J, Guo Y, et al.E3 ubiquitin ligase WWP2 as a promising therapeutictarget for diverse human diseases［J］．Mol Aspects Med, 2024;96:101257.PMID:38430667
[12] Xue C, Meng H, Niu W, et al. TRIM28 promotes tumor growth and metastasisin breast cancer by targeting the BRD7 protein for ubiquitination and degradation［J］．Cell Oncol (Dordr). 2024 Sep 2. PMID: 39222175
[13] 宋筱羽，肖斌，陆景润，等．CBL通过泛素化降解NCK2抑制乳腺癌细胞的增殖和侵袭［J］．南方医科大学学报，2022 ,42 (11)：1594-1603.
[14] Wang G, Zhuang Z, Shen S, et al.Regulation of PTEN and ovarian cancerprogression by an E3 ubiquitin ligase RBCK1［J］．Hum Cell, 2022,35(3):896-908.PMID: 35174471.
[15] Zhao H, Bi F, Li M,et al. E3 ubiquitin ligase RNF180 impairs IPO4/SOX2complex stability and inhibits SOX2-mediated malignancy in ovarian cancer［J］．Cell Signal,2024，113:110961.PMID: 37923100.
[16] Wu J, Wu Y, Chen S,et al.PARP1-stabilised FOXQ1 promotes ovarian cancerprogression by activating the LAMB3/WNT/β-catenin signalling pathway［J］．Oncogene,2024，43(12):866-883.PMID: 38297082.
[17] Hu X, Meng Y, Xu L, et al. Cul4 E3 ubiquitin ligase regulates ovarian cancerdrug resistance by targeting the antiapoptotic protein BIRC3［J］．Cell DeathDis,2019，10(2):104.PMID: 30718461.
[18] Hu J, Meng Y, Zeng J, et al. Ubiquitin E3 Ligase MARCH7 promotesproliferation and invasion of cervical cancer cells through VAV2-RAC1-CDC42pathway［J］．Oncol Lett,2018，16(2):2312-2318.PMID: 30008934.
[19] Huang X, Huo L, Xiao B, et al. Activating STING/TBK1 suppresses tumorgrowth via degrading HPV16/18 E7 oncoproteins in cervical cancer［J］．Cell DeathDiffer,2024，31(1):78-89.PMID: 38007552.
[20] Hu J, Meng Y, Zeng J, et al. Ubiquitin E3 Ligase MARCH7 promotesproliferation and invasion of cervical cancer cells through VAV2-RAC1-CDC42pathway［J］．Oncol Lett,2018，16(2):2312-2318.PMID: 30008934.
[21] Li J, Wang X, Zhang Y, et al.E3 ubiquitin ligase isolated by differential displayregulates cervical cancer growth in vitro and in vivo via microRNA-143［J］．ExpTher Med,2016,12(2):676-682. PMID: 27446260.
[22] Pavlides SC, Huang KT, Reid DA, et al. Inhibitors of SCF-Skp2/Cks1 E3ligase block estrogen-induced growth stimulation and degradation of nuclearp27kip1:therapeutic potential for endometrial cancer［J］．Endocrinology,2013,154(11):4030-4045.PMID: 24035998.
[23] Qi Y, Rezaeian AH, Wang J, et al.Molecular insights and clinical implications forthe tumor suppressor role of SCFFBXW7 E3 ubiquitin ligase［J］．Biochim BiophysActa Rev Cancer,2024，1879(5):189140. PMID: 38909632.
[24] Zhang H, Zhao Y, Wang J, et al. FBXO7, a tumor suppressor in endometrialcarcinoma, suppresses INF2-associated mitochondrial division［J］．Cell DeathDis,2023，14(6):368.PMID: 37344480.
[25] Zhou Q, Eldakhakhny S, Conforti F, et al. Pir2/Rnf144b is a potentialendometrial cancer biomarker that promotes cell proliferation［J］．Cell DeathDis,2018，9(5):504. PMID: 29724995.
[26] Zhang Y, Goodfellow R, Li Y, et al. NEDD4 ubiquitin ligase is a putativeoncogene in endometrial cancer that activates IGF-1R/PI3K/Akt signaling［J］．Gynecol Oncol,2015，139(1):127-133.PMID: 26193427.
[27] Yang B, Ke W, Wan Y,et al.Targeting RNF8 effectively reverses cisplatinand doxorubicin resistance in endometrial cancer［J］．Biochem Biophys ResCommun,2021，545:89-97.PMID: 33548629.
[28] Lepage CC, Palmer MCL, Farrell AC, et al. Reduced SKP1 and CUL1 expressionunderlies increases in Cyclin E1 and chromosome instability in cellular precursorsof high-grade serous ovarian cancer［J］．Br J Cancer. 2021，124(10):1699-1710.PMID: 33731859.