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Volume 2,Issue 1

Fall 2025

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25 March 2025

山茶(Camellia japonica)花提取物在干性敏感皮肤中的舒缓修护功效研究

建华 张1 文姣 郭1 娜 李1 青云 董2、3 垠 吴2 亚利 张2
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1 1. 诺德溯源(广州)生物科技有限公司, 1. 诺德溯源(广州)生物科技有限公司
2 2. 上海市农业科学院林木果树研究所, 2. 上海市农业科学院林木果树研究所
3 3. 北京林业大学园林学院, 3. 北京林业大学园林学院
CDCST 2025 , 2(1), 73–78; https://doi.org/10.61369/CDCST.10460
© 2025 by the Author. Licensee Art and Design, USA. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

评估山茶花提取物(CJFE)及含有其的面霜在体内外的舒缓修护功效。体外结果:CJFE显著抑制TRPV1的表达(P<0.05),降低斑马鱼皮肤屏障通透性(P<0.05)。含3 wt%CJFE的面霜使3D表皮模型活细胞层厚度增加,促进丝聚蛋白(FLG)和兜甲蛋白(LOR)生成。临床结果:干敏志愿者使用该面霜4周后,面部MMV和TEWL值显著改善(p<0.05),a*值和敏感性显著降低(P<0.05)。本研究表明CJFE具备舒缓修护功效,适用于干敏皮肤,为山茶花在化妆品领域的应用提供了依据。

Keywords
山茶花
敏感性皮肤
TRPV1
屏障
References

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