微藻源甘油葡糖苷抗炎舒缓及屏障修护功效评价
微藻源甘油葡糖苷（Glycerolglucoside, GG）是一种具备多种功效的化妆品原料，本文通过细胞实验和3D皮肤模型等实验研究了甘油葡糖苷的抗炎特性。结果表明，GG可显著降低LPS诱导RAW264.7细胞分泌的IL-1β和IL-6释放量，证明了GG具有抗炎的作用。在GG浓度为3%时，肥大细胞脱颗粒率降低了87.88%，证明GG具有舒缓功效。基于3D表皮皮肤模型验证了GG可明显改善角质层疏松情况，并能够降低炎症因子IL-1α和PGE2的表达量。通过TGM1&LOR基因表达结果显示，GG可以显著增强角质细胞屏障功能；采用细胞迁移划痕实验同样证明了GG具有良好的细胞修复功效。
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