ARTICLE
5 March 2026

罗马洋甘菊挥发油脂质体凝胶对特应性皮炎的治疗作用研究

军 程1 大存 张2 春风 汪2 晗璐 胡1 雪 钱1 斌 陈1 国庆 陈2
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1 中华全国供销合作总社南京野生植物综合利用研究所, 中国
2 山东九鑫生物工程有限公司, 中国
CDCST 2026 , 3(1), 80–84; https://doi.org/10.61369/CDCST.2026010015
© 2026 by the authors. Licensee Art and Technology, USA. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

本研究旨在制备白及多糖包裹的罗马洋甘菊挥发油脂质体凝胶(CNVO-LG),探究其对小鼠AD的治疗效果。结果表明,罗马洋甘菊挥发油脂质体平均粒径145.6 nm,多分散系数为0.195,大小均一;脂质体凝胶呈疏松多孔网络结构。小鼠AD模型试验表明,CNVO-LG可显著改善AD小鼠的皮肤损状态,同时有效抑制AD小鼠皮肤和血清中IgG、TNFα、IL-4以及IFNγ等细胞因子水平。综上,罗马洋甘菊挥发油脂质体凝胶在治疗AD方面展现出较大应用潜力,为AD治疗提供了潜在方案。

Keywords
罗马洋甘菊
挥发油
脂质体凝胶
特应性皮炎
References

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