[1]Roelants Sophie L K W, Soetaert Wim.Industrial Perspectives for (Microbial) Biosurfactants[J].Advances in biochemical engineering/ biotechnology.2022,181.

[2]Zhao R ,She J,Jia Y.Challenges and Countermeasures of Daily Chemical Packaging under the Target of “Double Carbon”[J]. Industry Science and Engineering.2024,1(1).

[3]Peng Y ,Totsingan F ,Meier R A M , et al.Sophorolipids: Expanding structural diversity by ring ‐opening cross ‐metathesis[J].European Journal of Lipid Science and Technology.2015,117(2):217-228.

[4]Phavit W ,Benjamin I ,James W .A review of sophorolipid production from alternative feedstocks for the development of a localized selection strategy[J].Journal of Cleaner Production.2021,319.

[5]Filbert T ,Fei L ,A. R G .Structure–Activity Relationship Assessment of Sophorolipid Ester Derivatives against Model Bacteria Strains[J].Mo lecules.2021,26(10):3021-3021.

[6]Muneer Q A ,Qinhong W ,Zongjie D .Sophorolipids bioproduction in the yeast Starmerella bombicola: Current trends and perspectives[J]. Bioresource technology.2021,346126593-126593.

[7]Shah H U M ,Sivapragasam M ,Moniruzzaman M , et al.Production of sophorolipids by Starmerella bombicola yeast using new hydrophobic substrates[J].Biochemical Engineering Journal.2017,12760-67.

[8]Lee Y ,Cha J Y ,Jeong S , et al.A novel sophorolipids extraction method by yeast fermentation process for enhanced skin efficacy[J]. Skin Research and Technology.2023,29(11):e13518-e13518.

[9]Lin B ,Wang J ,Zha J , et al.Development of green solubilizer based on acidic sophorolipid[J].Journal of Surfactants and Detergents.2025,28(4):861-870.

[10]Priyanka D ,Hakon H ,Maria T , et al.Toward green flotation: Interaction of a sophorolipid biosurfactant with a copper sulfide[J]. Journal of Colloid And Interface Science.2021,585386-399.

[11]Jiménez-Peñalver P ,Castillejos M ,Koh A , et al.Production and characterization of sophorolipids from stearic acid by solid-state fermentation, a cleaner alternative to chemical surfactants[J].Journal of Cleaner Production.2018,1722735-2747.

[12]Aoki Y ,Asada T ,Nojiri M , et al.Comparative Analysis of Plant Defense Activation by Four Biosurfactants: Mode of Action and Disease Control Potential[J].International Journal of Molecular Sciences.2025,26(17):8313-8313.

[13]Ahuekwe F E ,Okoli E B ,Stanley H O , et al.Experimental Investigation of Sophorolipid Biosurfactants Produced by Candida and Pleurotus Species Using Waste Oils and Rice Bran and Their Oilfield Benefits[J].Journal of Advances in Biology & Biotechnology.2016,1-15.

[14]Jingyang L ,Bowen Y ,Xiaoling Y , et al.Sophorolipid-based microemulsion delivery system: Multifaceted enhancement of physicochemical properties of xanthohumol[J].Food Chemist ry.2023,413135631-135631.

[15]Gu X ,Li D ,Yuan H , et al.Tertiary/quaternary amine derivatives of sophorolipid for baicalin solubility and antioxidating performance improvement: solubilization or hydrotropy?[J].Journal of Molecular Liquids.2024,397124122.

[16]Y. W ,J. C ,X. L .A Review on Antimicrobial Activity, Anti-Biofilm and Synergistic Effects of Sophorolipids Since Their Discovery[J]. Applied Biochemistry and Microbiology.2023,59(5):580-596.

[17]Yan W C ,Fei J N ,Hsum W Y , et al.Sophorolipids—Bio-Based Antimicrobial Formulating Agents for Applications in Food and Health[J].Molecules.2022,27(17):5556-5556.

[18]Sahadevan S ,Rafaela F ,Melike P , et al.Acidic sophorolipid and antimicrobial peptide based formulation as antimicrobial and antibiofilm agents[J].Biomaterials Advances.2023,146213299-213299.

[19]Zhao Z ,Wu F ,Sun J , et al.Metagenomic insights into the mechanism of sophorolipid in facilitating co-anaerobic digestion of mushroom residues and cattle manure: Functional microorganisms and metabolic pathway analysis[J].Journal of Environmental Manageme nt.2024,370123048-123048.

[20]A G A ,S A A ,U M N , et al.The mechanistic interplay between Nrf-2, NF-κB/MAPK, caspase-dependent apoptosis, and autophagy in the hepatoprotective effects of Sophorolipids produced by microbial conversion of banana peels using Saccharomyces cerevisiae against doxorubicin-induced hepatotoxicity in rats[J].Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.2023,182114119-114119.

[21]Ruiqi X ,Ling M ,Timson C , et al.Sophorolipid Suppresses LPS-Induced Inflammation in RAW264.7 Cells through the NF-κB Signaling Pathway[J].Molecules.2022,27(15):5037-5037.

[22]Junguo H ,Jian T ,Tiantian L , et al.Removal of heavy metals in the presence of the biodegradable biosurfactant of sophorolipid from the municipal dewatered sludge[J].DESALINATION AND WATER TREATMENT.2017,225-232.

[23]S. C M ,K. P B .Review on sophorolipids – a promising microbial bio-surfactant[J].Tenside Surfactants Detergents.2023,60(2):95-105.

[24]Niki B ,Alexandre P ,Patrick G L , et al.Aqueous self-assembly of a wide range of sophorolipid and glucolipid microbial bioamphiphiles (biosurfactants): Considerations on the structure-properties relationship[J].Colloids and Surfaces A: Physicochemical and Engineering Aspects.2023,679.

[25]A N I B V ,L S M D ,Dirk D , et al.Development of a transformation and selection system for the glycolipid-producing yeast Candida bombicola.[J].Yeast (Chichester, England).2008,25(4):273-8.

[26]Lin Y ,Chen Y ,Li Q , et al.Rational high-throughput screening system for high sophorolipids production in Candida bombicola by co-utilizing glycerol and glucose capacity[J].Bioresources and Bioprocessing.2019,6(1):1-9.

[27]Chen Y ,Tian X ,Li Q , et al.Target-site directed rational high-throughput screening system for high sophorolipids production by Candida bombicola[J].Bioresource Technolo gy.2020,315123856-123856.

[28]Zhang M M ,Chen Z W ,Zhang P L , et al.Knockout mutation to enhance sophorolipid production in Starmerella bombicola based on computational structural analysis of fatty acid oxidation enzymes[J]. International journal of biological macromolecules.2025,307(Pt 4):142104.

[29]Xiao-Jing M ,Hui-Min Z ,Xu-Feng L , et al.Mutant breeding of Starmerella bombicola by atmospheric and room-temperature plasma (ARTP) for improved production of specific or total sophorolipids[J]. Bioprocess and biosystems engineering.2020,43(10):1-15.

[30]Saerens KM, Van Bogaert IN, Soetaert W. Characterization of sophorolipid biosynthetic enzymes from Starmerella bombicola[J]. FEMS Yeast Res. 2015 ,15(7):75.

[31]Ciesielska K, Roelants SL, Van Bogaert IN, De Waele S, Vandenberghe I, Groeneboer S, Soetaert W, Devreese B. Characterization of a novel enzyme-Starmerella bombicola lactone esterase (SBLE)-responsible for sophorolipid lactonization[J]. Appl Microbiol Biotechnol. 2016 ,100(22):9529-9541.

[32]Li J, Xia C, Fang X, Xue H, Song X. Identification and characterization of a long-chain fatty acid transporter in the sophorolipid-producing strain Starmerella bombicola[J]. Appl Microbiol Biotechnol. 2016,100(16):7137-50.

[33]Fumikazu T ,Kazuaki I ,Hiroshi H .Identification of the fatty alcohol oxidase FAO1 from Starmerella bombicola and improved novel glycolipids production in an FAO1 knockout mutant[J].Applied microbiology and biotechnology.2016,100(22):9519-9528.

[34]Kao Corporation; Patent Issued for Sophorolipid Highly- Productive Mutant Strain (USPTO 10,435,684)[J].Biotech Business Week.2019.

[35]Ma Y ,Chen X ,Shen W , et al.Metabolic engineering of Starmerella bombicola for the production of sophorolipids[J].Systems Microbiology and Biomanufacturing.2025,(prepublish):1-9.

[36]Jun L ,Jiashan L ,Na G , et al.Identification and characterization of a protein Bro1 essential for sophorolipids synthesis in Starmerella bombicola[J].Journal of industrial microbiology & biotechnolo gy.2020,47(4-5):1-12.

[37]广州立白企业集团有限公司.一种高产槐糖脂的基因敲除工程菌及其构建方法和应用:202211292334.1[P].2023-03-28.

[38]广州立白企业集团有限公司.一种高效构建多基因改造酵母菌的方法及其应用:202311347892.8[P].2024-02-06.

[39]广州立白企业集团有限公司.高产中短链内酯型槐糖脂的工程菌株及其构建方法和应用:202311580035.2[P].2024-02-13.

[40]广州立白企业集团有限公司.熊蜂生假丝酵母工程菌及其构建方法和应用:202410842538.0[P].2024-10-01.

[41]Yaguang Z ,Dan J ,Wanqi S , et al.Semicontinuous sophorolipid fermentation using a novel bioreactor with dual ventilation pipes and dual sieve-plates coupled with a novel separation system[J].Microbial biotechnology.2018,11(3):455-464.

[42]Renjun G ,Mia F ,Xuebing X , et al.Production of sophorolipids with enhanced volumetric productivity by means of high cell density fermentation[J].Applied microbiology and biotechnolo gy.2013,97(3):1103-11.

[43]Maddikeri L G ,Gogate R P ,Pandit B A .Improved synthesis of sophorolipids from waste cooking oil using fed batch approach in the presence of ultrasound[J].Chemical Engineering Journal.2015,263479-487.

[44]Dharini S S ,N. S M ,P. A P .Improved synthesis of sophorolipid biosurfactants using industrial by-products and their practical application[J].Tenside Surfactants Detergents.2022,59(1):17-30.

[45]Jeong-Hun K ,Yu-Ri O ,Juyoung H , et al.Value-added conversion of biodiesel into the versatile biosurfactant sophorolipid using Starmerella bombicola[J].Cleaner Engineering and Technology.2020,1.

[46]Wang H ,Tsang C ,To H M , et al.Techno-economic evaluation of a biorefinery applying food waste for sophorolipid production – A case study for Hong Kong[J].Bioresource Technology.2020,303122852.

[47]Phavit W ,Magda C ,Ben D , et al.Food processing by-products as sources of hydrophilic carbon and nitrogen for sophorolipid production[J].Resources, Conservation & Recycling.2022,185.

[48]Oiza N ,Vico M J ,S醤chez A , et al.Enhanced anaerobic digestion of food waste using purified lactonic sophorolipids produced by solid-state fermentation of molasses and oil waste: A circular approach[J]. Journal of Cleaner Production.2024,468143062-143062.

[49]Mu駉z E E ,Wongsirichot P ,Ingham B , et al.Screening of alternative nitrogen sources for sophorolipid production through submerged fermentation using Starmerella bombicola[J].Waste management (New York, N.Y.).2024,18623-34.

[50]Jia X ,Qi L ,Zhang Y , et al.Computational fluid dynamics simulation of a novel bioreactor for sophorolipid production[J].Chinese Journal of Chemical Engineering.2017,25(06):732-740.

[51]Van Renterghem L, Roelants SLKW, Baccile N, et al. From lab to market: An integrated bioprocess design approach for new-to-nature biosurfactants produced by Starmerella bombicola[J]. Biotechnol Bioeng. 2018,115(5):1195-1206.

[52]FengY ,WangR ,AnZ , et al.Optimization of temperature shift-based fermentation process for sophorolipids production using response surface methodology[J].AIP Conference Proceedings. 2019,2110(1):020002.

[53]Kim JH, Oh YR, Han SW, et al. Enhancement of sophorolipids production in Candida batistae, an unexplored sophorolipids producer, by fed-batch fermentation[J]. Bioprocess Biosyst Eng. 2021,44(4):831-839.

[54]Haojie L ,Aiyong H ,Shun L , et al.Efficient production of acidic sophorolipid from rapeseed oil by Candida bombicola[J].Biofuels, Bioproducts and Biorefining. 2022,16(4):1050-1061.

[55]Xu F, Chen Y, Zou X, et al. Precise fermentation coupling with simultaneous separation strategy enables highly efficient and economical sophorolipids production[J]. Bioresour Technol. 2023,388:129719.

[56]Chen Y, Tang X, Li Y,et al. Ultrasound assisted in situ separation of sophorolipids in multi-phase fermentation system to achieve efficient production by Candida bom bicola[J]. Biotechnol J. 2022,17(2):e2100478.

[57]Dolman M B ,Kaisermann C ,Martin J P , et al.Integrated sophorolipid production and gravity separation[J].Process Biochemistry. 2017,54162-171.

[58]Zulkifli M W F N W ,Razak A N N ,Yatim M R A , et al.Acid Precipitation versus Solvent Extraction: Two Techniques Leading to Different Lactone/Acidic Sophorolipid Ratios[J].Journal of Surfactants and Detergents. 2019,22(2):365-371.

[59]Yogita P ,N. S M ,B. S K , et al.Improved adsorptive purification and effective separation of acidic and lactonic sophorolipid biosurfactant[J].Journal of the Indian Chemical Society.2022,99(11).

[60]Ma飐sa D ,M R M ,Johannes F , et al.Seeking faster, alternative methods for glycolipid biosurfactant characterization and purification[J]. Analytical and bioanalytical chemistry.2021,413(16):1-10.

[61]Pinky Samtani, et al.”Fermentative Production of Sophorolipid and Purification by Adsorption Chromatography[J].Tenside Surfactants Detergents.2018,55.(6):467-476.

[62]Tang Y ,Ma Q ,Du Y , et al.Efficient purification of sophorolipids via chemical modifications coupled with extractions and their potential applications as antibacterial agents[J].Separation and Purification Techn ology.2020,245(prepublish).

[63]Zehua Q ,Wei G ,Jun L, et al.Reduced-Cost Production of Sophorolipids by Starmerella bombicola CGMCC1576 Grown on Cottonseed Molasses and Cottonseed Oil-Based Medium[J]. International Journal of Molecular Sciences.2023,24(6):5759-5759.

[64]A N I B V ,Dieter B ,C J M , et al.Synthesis of bolaform biosurfactants by an engineered Starmerella bombicola yeast[J]. Biotechnology and bioengineering.2016,113(12):2644-2651.

[65]广州立白企业集团有限公司.一种含槐糖脂的机洗洗碗液组合物及其制备方法与应用:202411493502.2[P].2025-01-28.

[66]Huang C ,Hu C ,Sun G , et al.Antimicrobial finish of cotton fabrics treated by sophorolipids combined with 1,2,3,4-butanetetracarboxyic acid[J].Cellulose.2020,27(5):2859-2872.

[67]AnnKathrin B ,Lars B ,Amira O , et al.Environmental Impacts of Biosurfactants from a Life Cycle Perspective: A Systematic Literature Review[J].Advances in biochemical engineering/ biotechnology.2022,181.

[68]Solaiman K D ,Ashby D R ,Uknalis J .Characterization of growth inhibition of oral bacteria by sophorolipid using a microplate-format assay[J].Journal of Microbiological Methods.2017,13621-29.

[69]M E ,I M ,H M , et al.Rhamnolipids and lactonic sophorolipids: natural antimicrobial surfactants for oral hygiene[J].Journal of applied microbiology.2017,123(5):1111-1123.