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20 December 2025

Clinical Observation of the Therapeutic Effect of Chrysanthemum Indicum Injection Combined with Budesonide Suspension Nebulization in the Treatment of Acute Suppurative Tonsillitis

Chunhai Lei1 Fei Xie1 Yanjin Yu*
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1 Department of Otolaryngology, Affiliated Hospital of Jiangxi University of CM, Nanchang 330000, Jiangxi, China
AMCMR 2025 , 1(4), 31–37; https://doi.org/10.61369/AMCMR.202504005
© 2025 by the Author. Licensee Art and Design, USA. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

Objective: To investigate the clinical efficacy of Chrysanthemum Indicum injection combined with Budesonide suspension nebulization in the treatment of acute suppurative tonsillitis. Methods: A total of 60 patients with acute suppurative tonsillitis admitted to our hospital from January 2021 to December 2022 were selected as the research subjects. Both groups received anti-inflammatory treatment with cefathiamidine. The control group (30 cases) also received dexamethasone nebulization therapy, while the treatment group (30 cases) received nebulization therapy with a combination of wild chrysanthemum injection and budesonide suspension. Before treatment, the age, gender, and clinical symptoms such as sore throat, tonsillar congestion, suppuration, fever, and cough of the patients were observed and recorded. The changes in clinical symptoms during the treatment period were continuously observed and recorded. On the day of treatment completion, the clinical symptoms of sore throat, tonsillar congestion, suppuration, fever, and cough were observed and recorded, and the number of patients who recovered was recorded. Results: Before treatment, there were no significant differences between the two groups of patients in terms of gender and age (p > 0.05). Additionally, there were no significant differences in the severity of symptoms such as sore throat, tonsillar congestion, purulence, fever, and cough (p > 0.05). After 3 days of treatment, symptoms like sore throat, tonsillar congestion, purulence, and cough were significantly alleviated, while fever showed no significant improvement. The total symptom scores between the groups were significantly different (p < 0.05). After 5 days of treatment, the clinical symptoms were further significantly improved, the total symptom scores remained significantly different (p < 0.05), and the number of patients who recovered increased significantly (p < 0.05). Conclusion: Nebulization therapy with a combination of wild chrysanthemum injection and budesonide suspension for acute suppurative tonsillitis is more effective than traditional dexamethasone nebulization therapy.

Keywords
Chrysanthemum indicum injection
Budesonide suspension
Dexamethasone
Acute suppurative tonsillitis
Funding
Science and Technology Program of Jiangxi Provincial Administration of Chinese Medicine (Project No.: 2022B655)
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